Hoof Wall Separation Disease
(from U.C. Davis website) “Hoof Wall Separation Disease (HWSD) is a genetic defect characterized by a hoof wall that easily breaks and cracks, and a normal appearing coronary band. The breaks and cracks begin to occur in young ponies. In severe cases the pony bears weight entirely on the sole of the foot which can lead to severe lameness. HWSD is inherited as an autosomal recessive trait. This means that carriers are completely normal and only animals with two copies of the mutation will show clinical signs of the disease. HWSD appears to occur only in the Connemara pony and the carrier frequency has been estimated to be about 14.8%. A DNA test for this specific mutation can determine if ponies are normal or if they carry one or two copies of the mutation. Ponies that carry two copies of the mutation are highly likely to be affected with the disease. Some cases are milder while others are more severe. We have identified at least one case where the pony does not appear to have clinical signs associated with having two copies of the mutation. This indicates that the mutation is not fully penetrant; however it has very high penetrance of 96.8%.
The VGL offers a DNA test for HWSD to assist owners and breeders in identifying affected and carrier ponies. The test uses DNA collected from mane hair thus avoiding invasive blood collection. Breeders can use results from the test as a tool for selection of mating pairs to avoid producing affected foals.”
If your pony has been DNA tested and the results are on file at UC Davis you may have your pony tested for HWSD using these samples. Please send the $40 fee to Marynell Eyles and she will request the hair be used for HWSD.